Network optimization data:
Effect of polymer temperature degradation.
It is rarely seen that the decomposition of materials has anything to do with temperature in experiments. This is because in vitro tests are usually conducted to simulate temperatures, which vary very little in the body. However, in the process of in vitro test, in order to meet the needs of the test, the temperature can be appropriately increased to shorten the test period. However, in the process of accelerated decomposition, the purpose of accelerated decomposition cannot be achieved when the temperature is too low, because the polymer will produce side reaction when the temperature is too high.
Therefore, in order to avoid the effects of temperature and air flow on the decomposed material, the decomposed material exists in a low-temperature sealed environment.
Effect of molecular weight on polymer degradation.
The hydrolysis rate of the fully degradable materials was significantly affected by the molecular weight and distribution of the copolymer. This is mainly because each ester bond can be hydrolyzed, and the hydrolysis of the ester bond on the molecular chain is irregular. The longer the molecular chain of the polymer, the more hydrolyzed part, the faster the decomposition.
Effect of polymer degradation on the structure of materials.
Anhydrides and esters readily hydrolyze.